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Anand, Nithya
- Comparative Evaluation of Periodontal Status and II-6 Levels in Chronic Kidney Disease Patients and Healthy Individuals
Authors
1 Post Graduate Student, Sree Balaji Dental College and Hospital, BIHER, Department of Periodontics and Implantology, Velachery Main Road, Pallikaranai, Chennai, Tamil Nadu, IN
2 Professor, Sree Balaji Dental College and Hospital, BIHER, Department of Periodontics and Implantology, Velachery Main Road, Pallikaranai, Chennai, Tamil Nadu, IN
3 Head of the Department, Sree Balaji Dental College and Hospital, BIHER, Department of Periodontics and Implantology, Velachery Main Road, Pallikaranai, Chennai, Tamil Nadu, IN
4 Reader, Sree Balaji Dental College and Hospital, BIHER, Department of Periodontics and Implantology, Velachery Main Road, Pallikaranai, Chennai, Tamil Nadu, IN
Source
Indian Journal of Public Health Research & Development, Vol 10, No 11 (2019), Pagination: 3268-3273Abstract
Background: Chronic kidney disease (CKD) is a veryreal and growing problem, as indicated by demographic trends. Presence of undiagnosed periodontitis may have significant effect on the medical management of CKD patient as its been found to contribute to systemic inflammatory burden.This study evaluate and compare the periodontal status and IL-6 levels among CKD, periodontitis and Healthy patients.
Materials and Method: Whole serum samples werecollected from 80 patients who were further divided into four groups; healthy (n=20), periodontitis (n=20), HD (n=20), PD (n=20). Serum IL-6 concentrations were determined by Standard enzyme -linked immunosorbent assay.
Results: Indicates the IL-6 levels in the studypopulation. The mean IL-6 value being highest in pre-dialysis (92.695) compared to dialysis (53.112), periodontitis (9.22) and healthy individuals (9.6). ANOVA results show a significant increase of IL-6 levels in the pre-dialysis group compared to alter groups. No significant change on PPD was appreciated.
Conclusion: Treatment of moderate to severeperiodontitis in ESRD populations will result in decreased IL-6 levels and, more importantly, decreased incidence of atherosclerotic complications awaits the result of interceptive clinical trials in this population
Keywords
Chronic Renal Disease, Periodontitis, Interleukin 6, End Stage Renal Disease, Dialysis, Periodontal Status.
- Estimation of Red Blood Cell Parameters and Serum Prohepcidin Level in Generalised Chronic Periodontitis Patients Before and After Non-Surgical Periodontal therapy
Authors
1 Department of Periodontology, Sree Balaji Dental College & Hospital, BIHER, Chennai, IN
2 Professor, Department of Periodontology, Sree Balaji Dental College & Hospital, BIHER, Chennai, IN
3 Post Graduate Student, Department of Periodontology, Sree Balaji Dental College & Hospital, BIHER, Chennai, IN
4 Professor & Head, Department of Periodontology, Sree Balaji Dental College & Hospital, BIHER, Chennai, IN
5 Reader, Department of Periodontology, Sree Balaji Dental College & Hospital, BIHER, Chennai, IN
Source
Indian Journal of Public Health Research & Development, Vol 10, No 11 (2019), Pagination: 3285-3290Abstract
Background: The Anaemia of chronic disease (ACD) is a prevalent, poorly understood condition that afflicts patients with a wide variety of diseases, including infections, malignancies and rheumatologic disorders.
Materials and Method: 40 patients 20-65 years of age with chronic periodontitis were assessed before and after periodontal therapy for Hb, ESR, Erythrocyte count, MCV, MCH, MCHC and PROHEPCIDIN (ELISA).
Results: A significant (p<.000) increase in RBC (4.581) and Hb (12.77) values were estimated after SRP compared to baseline. Prohepcidin levels decreased insignificantly after SRP. Tailed t test results shows significant correlation at the 0.01 level between RBC parameters but no significance between probing depth or prohepcidin values with RBC parameters.
Conclusion: The results conclude that reduction in periodontal inflammation by scaling and ischolar_main planning improves RBC count and hemoglobin level significantly Prohepcidin levels decreases with periodontal treatment but rather insignificantly.